Our services
We design and deliver RWE studies that generate robust, meaningful evidence from real-world settings — using validated tools, wearables, and remote data collection to capture outcomes as they happen.
Real-world evidence studies demand flexibility, scale, and precision. We support sponsors, academic institutions, and industry partners in generating high-quality RWE through open-label trials, longitudinal observational studies, and technology-enabled data collection — all delivered remotely.
Our remote-first infrastructure means participants can be recruited and followed up from anywhere in the UK, with validated outcome measures, wearable integration, and at-home testing built in from the start.
Study types
Open-label trials, longitudinal observational, patient registries, and pragmatic studies
Data sources
ePRO, wearables, cognitive assessments, at-home biomarker testing, and validated questionnaires
Compliance
GCP-aligned operations, full GDPR compliance, and UK-based data residency
Delivery
End-to-end management — study design through final analysis and reporting
From study design to final report, we manage every operational aspect of your RWE study.
RWE-specific study design, outcome measure selection, protocol and analysis plan drafting, ethics submission, and study registration.
ePRO and eDiary capture, validated cognitive and patient-reported outcome measures, wearable device integration, and at-home biomarker testing kits.
Real-time data quality monitoring via Trialflare, remote participant support, query management, and protocol deviation tracking throughout the study.
Statistical analysis to the pre-agreed SAP, benefit-risk assessment where required, and a comprehensive final study report ready for publication or regulatory review.
A typical real-world evidence study with Comet Clinical follows four clear phases.
Research question & design
We work with you to define the research question, select appropriate outcome measures and data sources, and develop a robust study protocol and analysis plan.
Ethics & setup
Ethics submission and approval, EDC build and validation, recruitment strategy activation, and participant onboarding via digital eConsent.
Data collection & monitoring
Remote data capture via ePRO, wearables, and at-home testing. Continuous data quality monitoring with real-time query resolution and participant support.
Analysis & reporting
Database lock, statistical analysis per the SAP, final report preparation, and archiving — with full audit trail maintained throughout.
Tell us about your research question and we'll talk through how Comet Clinical can design and deliver it.
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