Our services
From protocol design to final report, we manage placebo-controlled and prospective clinical trials without the overhead of traditional site-based delivery.
We support sponsors and academic institutions running non-CTIMP placebo-controlled and other prospective clinical trials. Our remote-first model removes geographic and logistical constraints while maintaining the highest standards of GCP compliance and regulatory rigour.
Every trial we run is designed for audit-readiness from day one — from ethics submission through to final archiving.
Study types
Non-CTIMP and selected CTIMP; placebo-controlled and open-label designs
Participants
UK and international recruitment via fully digital screening and onboarding
Compliance
Full GCP, GDPR, and ICH E6(R3) — audit-ready from day one
Delivery
End-to-end management — protocol through final report and archive
We take care of the full operational scope so your team can focus on the science.
Custom protocol and SAP drafting, IRAS ethics submissions, and trial registration on ISRCTN or ClinicalTrials.gov.
Independent randomisation schemes, allocation concealment, placebo management, and clear unblinding procedures when required.
Trialflare-powered EDC with AI-assisted build, eConsent, validated questionnaires, cognitive assessments, and real-time data monitoring.
Statistical analysis to the pre-agreed SAP, interim and final study reports, and regulatory submission support where needed.
A typical placebo-controlled study with Comet Clinical follows four clear phases.
Protocol, design & ethics
We work with you to finalise the study design, draft the protocol and randomisation plan, prepare patient-facing documents, and submit to the relevant ethics committee via IRAS.
Setup & recruitment
EDC and eConsent built and validated, recruitment strategy activated, participants screened remotely, and randomised to active or placebo arms.
Remote data collection & monitoring
Participants complete assessments, diaries, and questionnaires at home. Our team monitors data quality in real time, resolving queries and supporting participants throughout.
Analysis, reporting & closeout
Database lock, unblinding, statistical analysis per the SAP, final report delivery, and full trial master file archiving to GCP standards.
Tell us about your study and we'll talk through how Comet Clinical can design and deliver it.
Schedule a consultation
